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Don't smoke. Nicotine and other chemicals in cigarettes and cigars raise your possibility for just a blood clot while you use injectable contraception.The chemical structure of xylazine intently resembles that of phenothiazines, tricyclic antidepressants, and clonidine. Xylazine is in a similar drug class as clonidine, lofexidine, and dexmedetomidi